2. Gene
  3. Nkx1-1 - NK1 homeobox 1 Gene

Nkx1-1 - NK1 homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sax2; Nkx-1.1

Gene ID: 672284 | Gene type: protein coding

About Nkx1-1

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including nervous system process; regulation of generation of precursor metabolites and energy; and regulation of glucose metabolic process. Predicted to be active in nucleus. Is expressed in brain. Orthologous to human NKX1-1 (NK1 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Nkx1-1 Products(2)

mRNA Protein Name
NM_011320.1 NP_035450.1 NK1 transcription factor-related protein 1
NM_011320.1 NP_035450.1 NK1 transcription factor-related protein 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within lipid metabolic process IMP
IMP: Inferred from mutant phenotype
21126319 MGI
acts upstream of or within nervous system process IMP
IMP: Inferred from mutant phenotype
17879320 MGI
acts upstream of or within regulation of generation of precursor metabolites and energy IMP
IMP: Inferred from mutant phenotype
17879320 MGI
acts upstream of or within regulation of glucose metabolic process IMP
IMP: Inferred from mutant phenotype
21126319 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NK1 transcription factor-related protein 1

NK1 transcription factor related, locus 1

homeobox protein SAX-2

spinal cord axial homeobox gene 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09325 NKX1-1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09326 NKX1-2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nkx1-1 NCBI NCBI:54729