Cers4 - ceramide synthase 4 Gene

Also Known as Trh1; Lass4; 2900019C14Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 67260

Summary

Enables sphingosine N-acyltransferase activity. Acts upstream of or within ceramide biosynthetic process. Located in endoplasmic reticulum. Is expressed in nervous system; nose; oral epithelium; and skin. Orthologous to human CERS4 (ceramide synthase 4). [provided by Alliance of Genome Resources, Apr 2022]

Cers4 Products (1)

mRNA	Protein	Name
NM_026058.4	NP_080334.3	ceramide synthase 4

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables sphingosine N-acyltransferase activity	IDA IDA: Inferred from direct assay	15823095	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within ceramide biosynthetic process	IDA IDA: Inferred from direct assay	12912983	MGI
acts upstream of or within sphingolipid biosynthetic process	IDA IDA: Inferred from direct assay	15823095	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	12912983	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
ceramide synthase 4	LAG1 homolog, ceramide synthase 4 LAG1 longevity assurance homolog 4 TRAM homolog 1 longevity assurance homolog 4 sphingosine N-acyltransferase CERS4 translocating chain-associating membrane protein homolog 1

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-133490A	ST1074	Inducer	99.41%	Unkown
HY-RS02539	CERS4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-133488	ST1072	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cers4	NCBI	NCBI:79603