CERS4 - ceramide synthase 4 Gene

Homo sapiens

Also known as Trh1; LASS4

Gene ID: 79603 | Gene type: protein coding

About CERS4

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:8,209,370-8,262,421 (from NCBI)

This gene has 16 transcripts (splice variants), 301 orthologues and 5 paralogues. Ubiquitous expression in thyroid (RPKM 13.9), prostate (RPKM 10.3) and 24 other tissues.

Summary

Enables sphingosine N-acyltransferase activity. Involved in ceramide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

CERS4 Products(1)

mRNA	Protein	Name
NM_024552.3	NP_078828.2	ceramide synthase 4

CERS4 Protein Structure

Homeobox

TRAM_LAG1_CLN8

0
100
200
300
394 a.a.

Protein Preferred Names

Protein Names

ceramide synthase 4

LAG1 homolog, ceramide synthase 4

Related Diseases

Diseases

Alias

Her2-Receptor Negative Breast Cancer

Dermatitis, Atopic, 2

Atopic Dermatitis 2	ATOD2
Dermatitis, Atopic, Susceptibility To, 2	Dermatitis, Atopic, 2, Susceptibility To
Dermatitis, Atopic 2	Dermatitis Atopic 2
Atopic Eczema	Dermatitis, Atopic, Type 2
Dermatitis, Atopic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-133490A	ST1074	Inducer	/	Unkown
HY-RS02539	CERS4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CERS4	VGNC	VGNC:60794
Canis familiaris	CERS4	VGNC	VGNC:39150
Rattus norvegicus	CERS4	RGD	RGD:1309303
Bos taurus	CERS4	VGNC	VGNC:27226
Mus musculus	CERS4	MGD	MGI:1914510
Macaca mulatta	CERS4	VGNC	VGNC:71077

Name
Email *

	Sorry, but the email address you supplied was invalid.