Frmd8 - FERM domain containing 8 Gene

Also Known as iTAP; 1200004M23Rik; 2310035N23Rik; 4931429L16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67457

Summary

Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be located in centriolar satellite; cytosol; and nucleoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including forelimb bud; otic capsule; and skeleton. Orthologous to several human genes including FRMD8 (FERM domain containing 8). [provided by Alliance of Genome Resources, Apr 2022]

Frmd8 Products (1)

mRNA Protein Name
NM_026169.4 NP_080445.1 FERM domain-containing protein 8

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
29897333 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
29897333 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

FERM domain-containing protein 8

  • iRhom tail-associated protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05106 FRMD8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Frmd8 NCBI NCBI:83786