Ttll4 - tubulin tyrosine ligase-like family, member 4 Gene

Also Known as mKIAA0173; 4632407P03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67534

Summary

Enables protein-glutamic acid Ligase activity and tubulin binding activity. Involved in peptidyl-glutamic acid modification. Acts upstream of or within protein polyglutamylation and regulation of blastocyst development. Located in 9+0 non-motile cilium and ciliary basal body. Orthologous to human TTLL4 (tubulin tyrosine Ligase like 4). [provided by Alliance of Genome Resources, Apr 2022]

Ttll4 Products (1)

mRNA Protein Name
NM_001014974.2 NP_001014974.1 tubulin monoglutamylase TTLL4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
26829768 MGI
enables protein-glutamic acid ligase activity IDA
IDA: Inferred from direct assay
17499049 MGI
enables tubulin binding IDA
IDA: Inferred from direct assay
21074048 MGI
enables tubulin-glutamic acid ligase activity IDA
IDA: Inferred from direct assay
17499049 MGI
Biological Process GO Annotation Evidence References Source
involved in peptidyl-glutamic acid modification IDA
IDA: Inferred from direct assay
26829768 MGI
acts upstream of or within protein polyglutamylation IDA
IDA: Inferred from direct assay
20530212 MGI
involved in protein polyglutamylation IDA
IDA: Inferred from direct assay
21074048 MGI
acts upstream of or within protein polyglutamylation IMP
IMP: Inferred from mutant phenotype
29593216 MGI
acts upstream of or within regulation of blastocyst development IMP
IMP: Inferred from mutant phenotype
29593216 MGI
Cellular Component GO Annotation Evidence References Source
located in 9+0 non-motile cilium IDA
IDA: Inferred from direct assay
17499049 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
17499049 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin monoglutamylase TTLL4

tubulin polyglutamylase TTLL4

  • polyglutamylase

  • protein monoglutamylase TTLL4

  • tubulin--tyrosine ligase-like protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15231 TTLL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttll4 NCBI NCBI:9654