TTLL4 - tubulin tyrosine ligase like 4 Gene
Species: Homo sapiens
About TTLL4
This gene has 21 transcripts (splice variants), 180 orthologues and 12 paralogues. Broad expression in testis (RPKM 10.4), brain (RPKM 3.1) and 24 other tissues.
Summary
Predicted to enable tubulin binding activity and tubulin-glutamic acid Ligase activity. Predicted to be involved in microtubule Cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within regulation of blastocyst development. Predicted to be located in cytosol. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022]
TTLL4 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_014640.5 | NP_055455.3 | tubulin monoglutamylase TTLL4 |
TTLL4 Protein Structure
TTL: Tubulin-tyrosine ligase family (655 - 940)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1199 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tubulin monoglutamylase TTLL4 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Nephronophthisis 2 |
|
|
| Fundus Dystrophy |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS15231 | TTLL4 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | TTLL4 | VGNC | VGNC:54382 |
| Bos taurus | TTLL4 | VGNC | VGNC:36492 |
| Felis catus | TTLL4 | VGNC | VGNC:80394 |
| Rattus norvegicus | TTLL4 | RGD | RGD:1594742 |
| Mus musculus | TTLL4 | MGD | MGI:1914784 |
| Macaca mulatta | TTLL4 | VGNC | VGNC:79758 |
| Others | TTLL4 | NCBI |
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