Dnajb11 - DnaJ heat shock protein family (Hsp40) member B11 Gene

Also Known as Dj9; ERdj3; ERj3p; ABBP-2; 1810031F23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67838

Summary

Enables signaling receptor binding activity and unfolded protein binding activity. Acts upstream of or within mRNA modification and negative regulation of neurogenesis. Located in cytoplasm; extracellular space; and nucleus. Is expressed in embryo. Human ortholog(s) of this gene implicated in polycystic kidney disease. Orthologous to human DNAJB11 (DnaJ heat shock protein family (HSP40) member B11). [provided by Alliance of Genome Resources, Apr 2022]

Dnajb11 Products (3)

mRNA Protein Name
NM_001190804.1 NP_001177733.1 dnaJ homolog subfamily B member 11 precursor
NM_001190805.1 NP_001177734.1 dnaJ homolog subfamily B member 11 precursor
NM_026400.5 NP_080676.3 dnaJ homolog subfamily B member 11 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11584023 MGI
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
20335479 MGI
enables unfolded protein binding IDA
IDA: Inferred from direct assay
11584023 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within mRNA modification IDA
IDA: Inferred from direct assay
11584023 MGI
acts upstream of or within negative regulation of neurogenesis IMP
IMP: Inferred from mutant phenotype
20335479 MGI
acts upstream of or within negative regulation of neurogenesis IPI
IPI: Inferred from physical interaction
20335479 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11584023 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
20335479 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11584023 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dnaJ homolog subfamily B member 11

  • APOBEC1-binding protein 2

  • DnaJ (Hsp40) homolog, subfamily B, member 11

  • ER-associated Hsp40 co-chaperone

  • ER-associated dnaJ protein 3

  • ER-resident protein ERdj3

  • endoplasmic reticulum DNA J domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03864 DNAJB11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnajb11 NCBI NCBI:51726