2. Gene
  3. Slc25a11 - solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 Gene

Slc25a11 - solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2oxoc; 2310022P18Rik

Gene ID: 67863 | Gene type: protein coding

About Slc25a11

Summary

Predicted to enable antiporter activity; dicarboxylic acid transmembrane transporter activity; and sulfur compound transmembrane transporter activity. Predicted to be involved in anion transport. Located in mitochondrial inner membrane. Is expressed in embryo. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SLC25A11 (solute carrier family 25 member 11). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a11 Products(1)

mRNA Protein Name
NM_024211.3 NP_077173.1 mitochondrial 2-oxoglutarate/malate carrier protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables oxoglutarate:malate antiporter activity IMP
IMP: Inferred from mutant phenotype
35507647 MGI
Biological Process GO Annotation Evidence Reference Source
involved in gluconeogenesis IMP
IMP: Inferred from mutant phenotype
35507647 MGI
involved in malate-aspartate shuttle IMP
IMP: Inferred from mutant phenotype
31217581 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in mitochondrial inner membrane IMP
IMP: Inferred from mutant phenotype
35507647 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial 2-oxoglutarate/malate carrier protein

OGCP

alpha-oxoglutarate carrier

solute carrier family 25 member 11

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13091 SLC25A11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a11 NCBI NCBI:8402