Dynll2 - dynein light chain LC8-type 2 Gene

Mus musculus

Also known as DLC8; Dlc2; DLC8b; 1700064A15Rik; 6720463E02Rik

Gene ID: 68097 | Gene type: protein coding

About Dynll2

Summary

Predicted to enable several functions, including dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and scaffold protein binding activity. Predicted to be involved in cilium assembly. Part of cytoplasmic dynein complex and Myosin V complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; sensory organ; and thymus primordium. Orthologous to human DYNLL2 (dynein light chain LC8-type 2). [provided by Alliance of Genome Resources, Apr 2022]

Dynll2 Products(3)

mRNA	Protein	Name
NM_001168471.1	NP_001161943.1	dynein light chain 2, cytoplasmic
NM_001168472.1	NP_001161944.1	dynein light chain 2, cytoplasmic
NM_026556.4	NP_080832.1	dynein light chain 2, cytoplasmic

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11546872	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of cytoplasmic dynein complex	IPI IPI: Inferred from physical interaction	25294941	MGI
part of myosin V complex	IDA IDA: Inferred from direct assay	14561217	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dynein light chain 2, cytoplasmic

8 kDa dynein light chain b

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04089	DYNLL2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dynll2	NCBI	NCBI:140735

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