Ncapd2 - non-SMC condensin I complex, subunit D2 Gene

Also Known as CNAP1; CAP-D2; mKIAA0159; 2810406C15Rik; 2810465G24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68298

Summary

Predicted to enable histone binding activity. Predicted to be involved in meiotic chromosome condensation and mitotic chromosome condensation. Predicted to act upstream of or within cell division and chromosome condensation. Located in condensed chromosome and pronucleus. Part of condensin complex. Is expressed in central nervous system; retina outer nuclear layer; and salivary gland. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD2 (non-SMC condensin I complex subunit D2). [provided by Alliance of Genome Resources, Apr 2022]

Ncapd2 Products (1)

mRNA Protein Name
NM_146171.1 NP_666283.1 condensin complex subunit 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of chromosome segregation IMP
IMP: Inferred from mutant phenotype
25474630 MGI
involved in positive regulation of chromosome separation IMP
IMP: Inferred from mutant phenotype
21795393 MGI
Cellular Component GO Annotation Evidence References Source
located in condensed chromosome IDA
IDA: Inferred from direct assay
12082153 MGI
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
25474630 MGI
part of condensin complex IDA
IDA: Inferred from direct assay
21795393 MGI
located in pronucleus IDA
IDA: Inferred from direct assay
12082153 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

condensin complex subunit 1

  • XCAP-D2 homolog

  • chromosome condensation-related SMC-associated protein 1

  • chromosome-associated protein D2

  • mCAP-D2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09066 NCAPD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncapd2 NCBI NCBI:9918