Lrrtm2 - leucine rich repeat transmembrane neuronal 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 685472

Summary

Enables neurexin family protein binding activity. Involved in regulation of postsynaptic density assembly. Acts upstream of or within synapse organization. Located in excitatory synapse. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and hippocampal mossy fiber to CA3 synapse. Is integral component of postsynaptic density membrane. Orthologous to human LRRTM2 (leucine rich repeat transmembrane neuronal 2). [provided by Alliance of Genome Resources, Apr 2022]

Lrrtm2 Products (1)

mRNA Protein Name
NM_001109469.1 NP_001102939.1 leucine-rich repeat transmembrane neuronal protein 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables neurexin family protein binding IPI
IPI: Inferred from physical interaction
21424692 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic density assembly IDA
IDA: Inferred from direct assay
19285470 RGD
involved in regulation of postsynaptic density assembly IMP
IMP: Inferred from mutant phenotype
19285470 RGD
acts upstream of or within synapse organization IDA
IDA: Inferred from direct assay
19285470 RGD
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
19285470 RGD
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
19285470 RGD
located in excitatory synapse IDA
IDA: Inferred from direct assay
19285470 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
19285470 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
19285470 RGD
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
19285470 RGD
is active in hippocampal mossy fiber to CA3 synapse IMP
IMP: Inferred from mutant phenotype
19285470 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
19285470 RGD
is active in postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
19285470 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane neuronal protein 2

  • leucine-rich repeat neuronal 2 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07842 LRRTM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrtm2 NCBI NCBI:26045