Sgo2a - shugoshin 2A Gene

Also Known as Sgol2; Sgol2a; Tripin; D1Ertd8e; 1110007N04Rik; 4932411A20Rik; 5730576N04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68549

Summary

Acts upstream of or within meiotic nuclear division; positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric; and protein localization. Located in kinetochore. Is expressed in nervous system and oocyte. Orthologous to human SGO2 (shugoshin 2). [provided by Alliance of Genome Resources, Apr 2022]

Sgo2a Products (4)

mRNA Protein Name
NM_001177867.1 NP_001171338.1 shugoshin 2 isoform 2
NM_199007.2 NP_950172.1 shugoshin 2 isoform 1
NM_001177867.1 NP_001171338.1 shugoshin 2 isoform 2
NM_199007.2 NP_950172.1 shugoshin 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21666598 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within female meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
18765791 MGI
acts upstream of maintenance of meiotic sister chromatid cohesion, centromeric IMP
IMP: Inferred from mutant phenotype
18765791 MGI
acts upstream of or within male meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
18765791 MGI
acts upstream of or within meiotic sister chromatid cohesion involved in meiosis I IMP
IMP: Inferred from mutant phenotype
25533956 MGI
acts upstream of or within meiotic sister chromatid cohesion, centromeric IMP
IMP: Inferred from mutant phenotype
18084284 MGI
acts upstream of or within positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric IMP
IMP: Inferred from mutant phenotype
18765791 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
18084284 MGI
Cellular Component GO Annotation Evidence References Source
located in chromosome, centromeric region IDA
IDA: Inferred from direct assay
17205076 MGI
located in condensed chromosome, centromeric region IDA
IDA: Inferred from direct assay
18084284 MGI
located in kinetochore IDA
IDA: Inferred from direct assay
18084284 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

shugoshin 2

  • sgo2

  • shugoshin-like 2

  • shugoshin-like 2a

Sgo2a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Sgo2 Q7TSY8 Mad2l1 Mus musculus Q9Z1B5
Anti Tag CoIP
21666598
Intra
Sgo2 Q7TSY8 Mad2l1 Mus musculus Q9Z1B5
Y2H
21666598
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12808 SGO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown