Sgo2a - shugoshin 2A Gene

Mus musculus

Also known as Sgol2; Sgol2a; Tripin; D1Ertd8e; 1110007N04Rik; 4932411A20Rik; 5730576N04Rik

Gene ID: 68549 | Gene type: protein coding

About Sgo2a

Summary

Acts upstream of or within meiotic nuclear division; positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric; and protein localization. Located in kinetochore. Is expressed in nervous system and oocyte. Orthologous to human SGO2 (shugoshin 2). [provided by Alliance of Genome Resources, Apr 2022]

Sgo2a Products(4)

mRNA	Protein	Name
NM_001177867.1	NP_001171338.1	shugoshin 2 isoform 2
NM_199007.2	NP_950172.1	shugoshin 2 isoform 1
NM_001177867.1	NP_001171338.1	shugoshin 2 isoform 2
NM_199007.2	NP_950172.1	shugoshin 2 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21666598	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within female meiotic nuclear division	IMP IMP: Inferred from mutant phenotype	18765791	MGI
acts upstream of maintenance of meiotic sister chromatid cohesion, centromeric	IMP IMP: Inferred from mutant phenotype	18765791	MGI
acts upstream of or within male meiotic nuclear division	IMP IMP: Inferred from mutant phenotype	18765791	MGI
acts upstream of or within meiotic sister chromatid cohesion involved in meiosis I	IMP IMP: Inferred from mutant phenotype	25533956	MGI
acts upstream of or within meiotic sister chromatid cohesion, centromeric	IMP IMP: Inferred from mutant phenotype	18084284	MGI
acts upstream of or within positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric	IMP IMP: Inferred from mutant phenotype	18765791	MGI
acts upstream of or within protein localization	IMP IMP: Inferred from mutant phenotype	18084284	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in chromosome, centromeric region	IDA IDA: Inferred from direct assay	17205076	MGI
located in condensed chromosome, centromeric region	IDA IDA: Inferred from direct assay	18084284	MGI
located in kinetochore	IDA IDA: Inferred from direct assay	18084284	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

shugoshin 2

sgo2	shugoshin-like 2
shugoshin-like 2a

Sgo2a Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Sgo2	Q7TSY8	Mad2l1	Mus musculus	Q9Z1B5	Anti Tag CoIP	21666598
Intra	Sgo2	Q7TSY8	Mad2l1	Mus musculus	Q9Z1B5	Y2H	21666598

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12808	SGO2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Name
Email *

	Sorry, but the email address you supplied was invalid.