Ubr3 - ubiquitin protein ligase E3 component n-recognin 3 Gene

Also Known as Zfp650; Znf650; 1110059H15Rik; 4833421P10Rik; A130030D10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68795

Summary

Enables ubiquitin protein Ligase activity. Involved in embryo development; sensory perception of smell; and ubiquitin-dependent protein catabolic process. Acts upstream of or within in utero embryonic development; olfactory behavior; and suckling behavior. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in cytoplasm. Is expressed in cranial ganglion and dorsal root ganglion. Orthologous to human UBR3 (ubiquitin protein Ligase E3 component n-recognin 3). [provided by Alliance of Genome Resources, Apr 2022]

Ubr3 Products (2)

mRNA Protein Name
NM_001303033.1 NP_001289962.1 E3 ubiquitin-protein ligase UBR3 isoform 3
NM_177783.6 NP_808451.2 E3 ubiquitin-protein ligase UBR3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17462990 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
17462990 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
17462990 MGI
Biological Process GO Annotation Evidence References Source
involved in embryo development ending in birth or egg hatching IMP
IMP: Inferred from mutant phenotype
17462990 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
17462990 MGI
acts upstream of or within olfactory behavior IMP
IMP: Inferred from mutant phenotype
17462990 MGI
involved in sensory perception of smell IMP
IMP: Inferred from mutant phenotype
17462990 MGI
acts upstream of or within suckling behavior IMP
IMP: Inferred from mutant phenotype
17462990 MGI
involved in suckling behavior IMP
IMP: Inferred from mutant phenotype
17462990 MGI
involved in ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
17462990 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase UBR3

  • N-recognin-3

  • RING-type E3 ubiquitin transferase UBR3

  • ubiquitin-protein ligase E3-alpha-3

  • ubiquitin-protein ligase E3-alpha-III

  • zinc finger protein 650

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15388 UBR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ubr3 NCBI NCBI:130507