Med27 - mediator complex subunit 27 Gene

Also Known as Crsp8; D2Ertd434e; 1500015J03Rik; 2310042P07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68975

Summary

Predicted to enable transcription coactivator activity. Predicted to contribute to ubiquitin protein Ligase activity. Acts upstream of or within stem cell population maintenance. Part of mediator complex. Is expressed in genitourinary system. Orthologous to human MED27 (mediator complex subunit 27). [provided by Alliance of Genome Resources, Apr 2022]

Med27 Products (4)

mRNA Protein Name
NM_001290489.1 NP_001277418.1 mediator of RNA polymerase II transcription subunit 27 isoform c
NM_001290490.1 NP_001277419.1 mediator of RNA polymerase II transcription subunit 27 isoform d
NM_026896.5 NP_081172.2 mediator of RNA polymerase II transcription subunit 27 isoform a
NM_029615.1 NP_083891.1 mediator of RNA polymerase II transcription subunit 27 isoform b
Biological Process GO Annotation Evidence References Source
acts upstream of or within somatic stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
20720539 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 27

  • CRSP complex subunit 8

  • cofactor required for Sp1 transcriptional activation, subunit 8

  • transcriptional co-activator CRSP8 homolog

Orthologs Information

Species Symbol Source ID
Homo sapiens Med27 NCBI NCBI:9442