Zdhhc3 - zinc finger, DHHC domain containing 3 Gene

Also Known as GODZ; DHHC-3; Gramp1; Zfp373; 1110020O22Rik; 1810006O10Rik; 2210017C02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69035

Summary

Enables protein homodimerization activity and protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; positive regulation of GABAergic synaptic transmission; and positive regulation of receptor localization to synapse. Acts upstream of or within protein targeting. Located in Golgi apparatus. Is expressed in early conceptus; genitourinary system; and ileum. Orthologous to human ZDHHC3 (zinc finger DHHC-type palmitoyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

Zdhhc3 Products (16)

mRNA Protein Name
NM_001372538.1 NP_001359467.1 palmitoyltransferase ZDHHC3 isoform 1
NM_001372539.1 NP_001359468.1 palmitoyltransferase ZDHHC3 isoform 2
NM_001372540.1 NP_001359469.1 palmitoyltransferase ZDHHC3 isoform 3
NM_001372541.1 NP_001359470.1 palmitoyltransferase ZDHHC3 isoform 4
NM_001372542.1 NP_001359471.1 palmitoyltransferase ZDHHC3 isoform 5
NM_001372543.1 NP_001359472.1 palmitoyltransferase ZDHHC3 isoform 6
NM_001372544.1 NP_001359473.1 palmitoyltransferase ZDHHC3 isoform 6
NM_001372546.1 NP_001359475.1 palmitoyltransferase ZDHHC3 isoform 7
NM_001372547.1 NP_001359476.1 palmitoyltransferase ZDHHC3 isoform 7
NM_001372548.1 NP_001359477.1 palmitoyltransferase ZDHHC3 isoform 8
NM_001372549.1 NP_001359478.1 palmitoyltransferase ZDHHC3 isoform 8
NM_001372550.1 NP_001359479.1 palmitoyltransferase ZDHHC3 isoform 8
NM_001372551.1 NP_001359480.1 palmitoyltransferase ZDHHC3 isoform 8
NM_001372552.1 NP_001359481.1 palmitoyltransferase ZDHHC3 isoform 8
NM_001372553.1 NP_001359482.1 palmitoyltransferase ZDHHC3 isoform 8
NM_026917.6 NP_081193.2 palmitoyltransferase ZDHHC3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables palmitoyltransferase activity IDA
IDA: Inferred from direct assay
15603741 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
23793055 MGI
enables protein-cysteine S-palmitoyltransferase activity IDA
IDA: Inferred from direct assay
19001095 MGI
Biological Process GO Annotation Evidence References Source
involved in peptidyl-L-cysteine S-palmitoylation IDA
IDA: Inferred from direct assay
23687301 MGI
involved in positive regulation of receptor localization to synapse IMP
IMP: Inferred from mutant phenotype
17151279 MGI
involved in positive regulation of synaptic transmission, GABAergic IMP
IMP: Inferred from mutant phenotype
17151279 MGI
acts upstream of or within protein palmitoylation IDA
IDA: Inferred from direct assay
15603741 MGI
involved in protein palmitoylation IDA
IDA: Inferred from direct assay
17151279 MGI
involved in protein palmitoylation IMP
IMP: Inferred from mutant phenotype
19001095 MGI
acts upstream of or within protein targeting IDA
IDA: Inferred from direct assay
12163046 MGI
involved in regulation of G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19001095 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12163046 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

palmitoyltransferase ZDHHC3

  • GABA-A receptor-associated membrane protein 1

  • acyltransferase ZDHHC3

  • golgi-specific DHHC zinc finger protein

  • zinc finger DHHC domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16021 ZDHHC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zdhhc3 NCBI NCBI:51304