Vps26b - VPS26 retromer complex component B Gene

Also Known as 1810012I05Rik; 2310075A12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69091

Summary

Involved in retrograde transport, endosome to Golgi. Acts upstream of or within cellular response to interferon-gamma. Located in early endosome; late endosome; and phagocytic vesicle. Part of retromer complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; male reproductive system; sensory organ; and urinary system. Orthologous to human VPS26B (VPS26, retromer complex component B). [provided by Alliance of Genome Resources, Apr 2022]

Vps26b Products (1)

mRNA Protein Name
NM_178027.4 NP_821170.1 vacuolar protein sorting-associated protein 26B

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
19144319 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
34965419 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: Inferred from mutant phenotype
34965419 MGI
involved in retrograde transport, endosome to Golgi IMP
IMP: Inferred from mutant phenotype
21920005 MGI
Cellular Component GO Annotation Evidence References Source
located in early endosome IDA
IDA: Inferred from direct assay
21920005 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
34965419 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
34965419 MGI
located in late endosome IDA
IDA: Inferred from direct assay
21920005 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
19144319 MGI
is active in postsynaptic early endosome IDA
IDA: Inferred from direct assay
34965419 MGI
is active in postsynaptic early endosome IMP
IMP: Inferred from mutant phenotype
34965419 MGI
is active in postsynaptic recycling endosome IDA
IDA: Inferred from direct assay
34965419 MGI
is active in postsynaptic recycling endosome IMP
IMP: Inferred from mutant phenotype
34965419 MGI
part of retromer complex IDA
IDA: Inferred from direct assay
21040701 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 26B

  • vacuolar protein sorting 26 homolog B

  • vesicle protein sorting 26B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15680 VPS26B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps26b NCBI NCBI:112936