2. Gene
  3. CARD8 - Nlrp1b NLR family, pyrin domain containing 1B Gene

CARD8 - Nlrp1b NLR family, pyrin domain containing 1B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as AABR07029890.1

Gene ID: 691998 | Gene type: protein coding

About CARD8

Summary

Predicted to enable several functions, including peptidase activator activity; protein domain specific binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of signal transduction; protein-containing complex assembly; and regulation of gene expression. Predicted to be located in nucleoplasm. Predicted to be part of CARD8 inflammasome complex and NLRP3 inflammasome complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in inflammatory bowel disease 30. Orthologous to human CARD8 (Caspase recruitment domain family member 8). [provided by Alliance of Genome Resources, Apr 2022]

CARD8 Products(1)

mRNA Protein Name
XM_008767925.3 XP_008766147.2 NACHT, LRR and PYD domains-containing protein 1b allele 3-like
Protein Preferred Names Protein Names

NACHT, LRR and PYD domains-containing protein 1b allele 3-like

NLR family, pyrin domain containing 1B

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-183739 CQ31 / Unkown
HY-185207 CQ80 Inducer / Unkown
HY-RS01922 CARD8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CARD8 NCBI NCBI:22900