Pacrg - PARK2 co-regulated Gene

Also Known as 1700008H23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69310

Summary

Enables ubiquitin protein Ligase binding activity. Involved in negative regulation of cell death. Acts upstream of or within cellular protein localization and spermatid development. Located in several cellular components, including cell body; manchette; and sperm midpiece. Is expressed in brain; pancreas trunk epithelium; and spinal cord ventricular layer. Orthologous to human PACRG (parkin coregulated). [provided by Alliance of Genome Resources, Apr 2022]

Pacrg Products (1)

mRNA Protein Name
NM_027032.2 NP_081308.1 parkin coregulated gene protein homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19805151 MGI
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
14532270 MGI
Biological Process GO Annotation Evidence References Source
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
37295417 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
25715396 MGI
acts upstream of or within spermatid development IGI
IGI: Inferred from genetic interaction
15148410 MGI
Cellular Component GO Annotation Evidence References Source
is active in axonemal B tubule inner sheath IDA
IDA: Inferred from direct assay
37295417 MGI
located in cell body IDA
IDA: Inferred from direct assay
19463890 MGI
located in cilium IDA
IDA: Inferred from direct assay
19463890 MGI
located in cytosol IDA
IDA: Inferred from direct assay
14532270 MGI
located in manchette IDA
IDA: Inferred from direct assay
25715396 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
14532270 MGI
is active in sperm flagellum IDA
IDA: Inferred from direct assay
37295417 MGI
located in sperm midpiece IDA
IDA: Inferred from direct assay
15148410 MGI
located in vesicle IDA
IDA: Inferred from direct assay
14532270 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

parkin coregulated gene protein homolog

  • PARK2 coregulated gene protein

  • hypertension-related protein 1-like protein

  • parkin co-regulated gene protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09954 PACRG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pacrg NCBI NCBI:135138