Tnfaip8l2 - tumor necrosis factor, alpha-induced protein 8-like 2 Gene

Mus musculus

Also known as TIPE2; 1810019A08Rik

Gene ID: 69769 | Gene type: protein coding

About Tnfaip8l2

Summary

Acts upstream of or within negative regulation of T cell activation and negative regulation of inflammatory response. Located in cytoplasm. Orthologous to human TNFAIP8L2 (TNF alpha induced protein 8 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Tnfaip8l2 Products(1)

mRNA	Protein	Name
NM_027206.3	NP_081482.1	tumor necrosis factor alpha-induced protein 8-like protein 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	18455983	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of T cell activation	IMP IMP: Inferred from mutant phenotype	21963221	MGI
acts upstream of or within negative regulation of T cell activation	IMP IMP: Inferred from mutant phenotype	21963221	MGI
acts upstream of or within negative regulation of inflammatory response	IMP IMP: Inferred from mutant phenotype	21466895	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	20663561	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tumor necrosis factor alpha-induced protein 8-like protein 2

TNF alpha-induced protein 8-like protein 2	TNFAIP8-like protein 2
tumor necrosis factor, alpha-induced protein 8-like protein 2

Tnfaip8l2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Tnfaip8l2	Q9D8Y7	Casp8	Mus musculus	O89110	Anti Bait CoIP	18455983

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14793	TNFAIP8L2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tnfaip8l2	NCBI	NCBI:79626

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