Znhit1 - zinc finger, HIT domain containing 1 Gene

Also Known as ZNFN4A1; 2700001K05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70103

Summary

Enables chromatin binding activity and histone deacetylase binding activity. Acts upstream of or within several processes, including negative regulation of G0 to G1 transition; negative regulation of transcription by RNA polymerase II; and regulation of histone deacetylation. Located in nucleus. Orthologous to human ZNHIT1 (zinc finger HIT-type containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Znhit1 Products (3)

mRNA Protein Name
NM_001310747.1 NP_001297676.1 zinc finger HIT domain-containing protein 1 isoform 2
NM_001310748.1 NP_001297677.1 zinc finger HIT domain-containing protein 1 isoform 3
NM_027318.4 NP_081594.1 zinc finger HIT domain-containing protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
19501046 MGI
enables histone deacetylase binding IPI
IPI: Inferred from physical interaction
19501046 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
29138493 MGI
Biological Process GO Annotation Evidence References Source
involved in calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
35167494 MGI
involved in chromatin remodeling IMP
IMP: Inferred from mutant phenotype
29138493 MGI
involved in heart process IMP
IMP: Inferred from mutant phenotype
35167494 MGI
involved in hematopoietic stem cell homeostasis IMP
IMP: Inferred from mutant phenotype
32694618 MGI
involved in intestinal stem cell homeostasis IMP
IMP: Inferred from mutant phenotype
30842416 MGI
acts upstream of or within negative regulation of G0 to G1 transition IDA
IDA: Inferred from direct assay
19501046 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19501046 MGI
involved in positive regulation of lymphoid progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
29138493 MGI
involved in positive regulation of transcription initiation by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
29138493 MGI
acts upstream of or within regulation of T cell proliferation IDA
IDA: Inferred from direct assay
19501046 MGI
involved in transcription initiation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
30842416 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
19501046 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger HIT domain-containing protein 1

  • p18 Hamlet

  • zinc finger protein, subfamily 4A (HIT domain containing), member 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16181 ZNHIT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21222 Znhit1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27738 Znhit1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Znhit1 NCBI NCBI:10467