2. Gene
  3. PDE5A - phosphodiesterase 5A Gene

PDE5A - phosphodiesterase 5A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 705592 | Gene type: protein coding

About PDE5A

Primary_assembly 5: 117,387,219-117,515,805 reverse strand.Mmul_10:CM014340.1

This gene has 2 transcripts (splice variants), 207 orthologues and 19 paralogues.

PDE5A Products(6)

mRNA Protein Name
XM_001099652.4 XP_001099652.2 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
XM_001099444.4 XP_001099444.2 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X3
XM_001099553.4 XP_001099553.4 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X2
XM_001099652.4 XP_001099652.2 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
XM_001099444.4 XP_001099444.2 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X3
XM_001099553.4 XP_001099553.4 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X2

PDE5A Protein Structure

GAF

GAF: smart00065 (163 - 320)

GAF

GAF: smart00065 (346 - 512)

PDEase_I

PDEase_I: pfam00233 (611 - 845)

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  • 800
  • 875 a.a.
Protein Preferred Names Protein Names

cGMP-specific 3',5'-cyclic phosphodiesterase

phosphodiesterase 5A, cGMP-specific

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-112831 Osoresnontrine Inhibitor 99.94% Phase 2
HY-170435 PDE5-IN-13 Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-106230A Dasantafil Inhibitor 98.35% Unkown
HY-N1343 Robustine Inhibitor 99.70% Unkown
HY-103084 PDE5-IN-1 Inhibitor / Unkown
HY-161851 MDL3 Inhibitor / Unkown
HY-N17363 Confusameline / Unkown
HY-RS10227 PDE5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10228 Pde5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10229 Pde5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE5A NCBI NCBI:8654
Mus musculus PDE5A NCBI NCBI:242202