Kdsr - 3-ketodihydrosphingosine reductase Gene

Also Known as Fvt1; 6330410P18Rik; 9430079B08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70750

Summary

Predicted to enable 3-dehydrosphinganine reductase activity. Acts upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 4 and follicular lymphoma. Orthologous to human KDSR (3-ketodihydrosphingosine reductase). [provided by Alliance of Genome Resources, Apr 2022]

Kdsr Products (2)

mRNA Protein Name
NM_001316750.1 NP_001303679.1 3-ketodihydrosphingosine reductase isoform 2 precursor
NM_027534.2 NP_081810.1 3-ketodihydrosphingosine reductase isoform 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within sphingolipid biosynthetic process IGI
IGI: Inferred from genetic interaction
15328338 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3-ketodihydrosphingosine reductase

  • 3-dehydrosphinganine reductase

  • KDS reductase

  • follicular lymphoma variant translocation 1

  • follicular variant translocation protein 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N10706 3-Keto sphinganine (d18:0) / Unkown
HY-RS07229 KDSR Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kdsr NCBI NCBI:2531