2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 3-Keto sphinganine (d18:0)

3-Keto sphinganine (d18:0) serves as the substrate for 3-keto-dihydrosphingosine reductase in the de novo sphingolipid synthesis pathway, and is a key intermediate in the de novo synthesis of sphingoid long-chain bases. 3-Keto sphinganine (d18:0) can be used in studies related to thrombocytopenia, anemia.

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3-Keto sphinganine (d18:0)

3-Keto sphinganine (d18:0) Chemical Structure

CAS No. : 16105-69-4

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3-Keto sphinganine (d18:0) Related Antibodies

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Description

3-Keto sphinganine (d18:0) serves as the substrate for 3-keto-dihydrosphingosine reductase in the de novo sphingolipid synthesis pathway, and is a key intermediate in the de novo synthesis of sphingoid long-chain bases. 3-Keto sphinganine (d18:0) can be used in studies related to thrombocytopenia, anemia[1].

In Vitro

3-Keto sphinganine (KDSR) (d18:0) levels are significantly reduced by expression of functional KDSR in propositus-derived iMK, with associated increases in sphingosine and decreases in ceramide levels but no change in DHS levels[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3-Keto sphinganine (d18:0) Related Antibodies
Molecular Weight

299.49

Formula

C18H37NO2
CAS No.
SMILES

O=C(C(CO)N)CCCCCCCCCCCCCCC
Structure Classification
Initial Source
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References
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3-Keto sphinganine (d18:0) Related Classifications

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Keywords:

3-Keto sphinganine (d18:0)16105-69-4Endogenous MetaboliteanemiaKDSRde novo sphingolipid synthesis pathwayerythrokeratodermia variabilis et progressiva 4sphingosineiMKceramideprogressive juvenile myelofibrosis3-keto-dihydrosphingosine reductasethrombocytopeniaInhibitorinhibitorinhibit

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