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Cat. No.: HY-N10706A

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3-Keto sphinganine (d18:0) hydrochloride

3-Keto sphinganine (d18:0) hydrochloride serves as the substrate for 3-keto-dihydrosphingosine reductase in the de novo sphingolipid synthesis pathway, and is a key intermediate in the de novo synthesis of sphingoid long-chain bases. 3-Keto sphinganine (d18:0) hydrochloride can be used in studies related to thrombocytopenia, anemia.

For research use only. We do not sell to patients.

CAS No.: 35299-94-6
Formula: C₁₈H₃₈ClNO₂
Molecular Weight:335.95

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

3-Keto sphinganine (d18:0) hydrochloride Chemical Structure

CAS No.: 35299-94-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
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Biological Activity

Description

All Endogenous Metabolite Isoforms :

In Vitro

3-Keto sphinganine (KDSR) (d18:0) hydrochloride levels are significantly reduced by expression of functional KDSR in propositus-derived iMK, with associated increases in sphingosine and decreases in ceramide levels but no change in DHS levels^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 35299-94-6
Appearance Solid
Molecular Weight 335.95
Formula C₁₈H₃₈ClNO₂
Color White to off-white
SMILES

O=C(CCCCCCCCCCCCCCC)C(N)CO.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (236 KB)
SDS (252 KB)
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- Norwegian - NO (252 KB)
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- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

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3-Keto sphinganine (d18:0) hydrochloride

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3-Keto sphinganine (d18:0) hydrochloride

All Endogenous Metabolite Isoforms

Biological Activity

Description

In Vitro

Chemical Information

Purity & Documentation

Calculators

Help & FAQs

3-Keto sphinganine (d18:0) hydrochloride Related Classifications

HY-N10706A Related Classifications

Bioz

Keywords

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