Spdya - speedy/RINGO cell cycle regulator family, member A Gene

Mus musculus

Also known as GS4; Spdy1; MLZ-465; 4921517J08Rik; 4930548B21Rik

Gene ID: 70891 | Gene type: protein coding

About Spdya

Summary

Enables protein kinase binding activity. Involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within male meiotic nuclear division. Located in nucleus. Is expressed in reproductive system. Orthologous to human SPDYA (speedy/RINGO cell cycle regulator family member A). [provided by Alliance of Genome Resources, Apr 2022]

Spdya Products(2)

mRNA	Protein	Name
NM_001142631.1	NP_001136103.1	speedy protein A isoform 2
NM_029254.1	NP_083530.1	speedy protein A isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein kinase activator activity	IDA IDA: Inferred from direct assay	28031483	MGI
enables protein kinase binding	IPI IPI: Inferred from physical interaction	15611625	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within establishment of protein localization to telomere	IMP IMP: Inferred from mutant phenotype	28031483	MGI
involved in male meiotic nuclear division	IEP IEP: Inferred from expression pattern	20339383	MGI
acts upstream of or within meiotic attachment of telomere to nuclear envelope	IDA IDA: Inferred from direct assay	28031483	MGI
acts upstream of or within meiotic attachment of telomere to nuclear envelope	IMP IMP: Inferred from mutant phenotype	28031483	MGI
acts upstream of or within oogenesis	IMP IMP: Inferred from mutant phenotype	28031483	MGI
involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	15611625	MGI
involved in positive regulation of protein kinase activity	IDA IDA: Inferred from direct assay	28031483	MGI
acts upstream of or within spermatogenesis	IMP IMP: Inferred from mutant phenotype	28031483	MGI
acts upstream of or within telomere capping	IMP IMP: Inferred from mutant phenotype	28031483	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in XY body	IDA IDA: Inferred from direct assay	28031483	MGI
located in chromosome, telomeric region	IDA IDA: Inferred from direct assay	28031483	MGI
located in nuclear envelope	IDA IDA: Inferred from direct assay	28031483	MGI
located in nucleus	IDA IDA: Inferred from direct assay	20339383	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

speedy protein A

RINGO A	mSpy/Ringo A
protein expressed in male leptotene and zygotene spermatocytes 465	rapid inducer of G2/M progression in oocytes A
speedy A	speedy A1
speedy A2	speedy homolog 1
speedy homolog A	speedy-1
spermatogenesis related protein Gs4	s

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13654	SPDYA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Spdya	NCBI	NCBI:245711

Name
Email *

	Sorry, but the email address you supplied was invalid.