Spdya - speedy/RINGO cell cycle regulator family, member A Gene

Also Known as GS4; Spdy1; MLZ-465; 4921517J08Rik; 4930548B21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70891

Summary

Enables protein kinase binding activity. Involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within male meiotic nuclear division. Located in nucleus. Is expressed in reproductive system. Orthologous to human SPDYA (speedy/RINGO cell cycle regulator family member A). [provided by Alliance of Genome Resources, Apr 2022]

Spdya Products (2)

mRNA Protein Name
NM_001142631.1 NP_001136103.1 speedy protein A isoform 2
NM_029254.1 NP_083530.1 speedy protein A isoform 1
Molecular Function GO Annotation Evidence References Source
enables protein kinase activator activity IDA
IDA: Inferred from direct assay
28031483 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
15611625 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within establishment of protein localization to telomere IMP
IMP: Inferred from mutant phenotype
28031483 MGI
involved in male meiotic nuclear division IEP
IEP: Inferred from expression pattern
20339383 MGI
acts upstream of or within meiotic attachment of telomere to nuclear envelope IDA
IDA: Inferred from direct assay
28031483 MGI
acts upstream of or within meiotic attachment of telomere to nuclear envelope IMP
IMP: Inferred from mutant phenotype
28031483 MGI
acts upstream of or within oogenesis IMP
IMP: Inferred from mutant phenotype
28031483 MGI
involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
15611625 MGI
involved in positive regulation of protein kinase activity IDA
IDA: Inferred from direct assay
28031483 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
28031483 MGI
acts upstream of or within telomere capping IMP
IMP: Inferred from mutant phenotype
28031483 MGI
Cellular Component GO Annotation Evidence References Source
located in XY body IDA
IDA: Inferred from direct assay
28031483 MGI
located in chromosome, telomeric region IDA
IDA: Inferred from direct assay
28031483 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
28031483 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20339383 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

speedy protein A

  • RINGO A

  • mSpy/Ringo A

  • protein expressed in male leptotene and zygotene spermatocytes 465

  • rapid inducer of G2/M progression in oocytes A

  • speedy A

  • speedy A1

  • speedy A2

  • speedy homolog 1

  • speedy homolog A

  • speedy-1

  • spermatogenesis related protein Gs4

  • s

Orthologs Information

Species Symbol Source ID
Homo sapiens Spdya NCBI NCBI:245711