INS-IGF2 - INS-IGF2 readthrough Gene

Also Known as INSIGF

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 723961

About INS-IGF2

This gene has 2 transcripts (splice variants). Biased expression in placenta (RPKM 1227.5) and liver (RPKM 104.8).

Summary

This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the Other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. [provided by RefSeq, Jul 2008]

INS-IGF2 Products (1)

mRNA Protein Name
NM_001042376.3 NP_001035835.1 insulin, isoform 2 precursor

INS-IGF2 Protein Structure

Insulin

Insulin: Insulin/IGF/Relaxin family (28 - 74)

  • 0
  • 100
  • 200 a.a.
Protein Preferred Names Protein Names

insulin, isoform 2

  • INS-IGF2 readthrough transcript protein

Related Diseases

Diseases Alias
Maturity-Onset Diabetes Of The Young, Type 10

  • Maturity-Onset Diabetes Of The Young Type 10

  • MODY10

  • Maturity-Onset Diabetes Of The Young 10

  • Mody-10

  • Mody Type 10

  • Diabetes Of The Young, Maturity-Onset, Type 10
Silver-Russell Syndrome 3

  • Growth Restriction, Severe, With Distinctive Facies

  • SRS3

  • Grdf
Diabetes Mellitus, Permanent Neonatal, 4

  • Diabetes Mellitus, Permanent Neonatal 4

  • PNDM4

  • Diabetes Mellitus, Permanent Neonatal, Type 4
Hyperproinsulinemia

  • HPRI
Type 1 Diabetes Mellitus 2

  • Diabetes Mellitus, Noninsulin-Dependent, 1

  • Diabetes Mellitus, Insulin-Dependent, 2

  • IDDM2

  • Insulin-Dependent Diabetes Mellitus 2

  • NIDDM1

  • Diabetes Mellitus, Noninsulin-Dependent 1

  • T1D2

  • Type 2 Diabetes Mellitus 1

  • T2D1

  • Noninsulin-Dependent Diabetes Mellitus 1

  • Diabetes Mellitus, Non-Insulin-Dependent, 1

  • Type 2 Diabetes Mellitus 1, Susceptibility To

  • Diabetes Mellitus, Insulin-Dependent, Type 2

  • Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Permanent Neonatal, 1

  • PNDM1

  • Pdmi

  • Dend Syndrome

  • Permanent Diabetes Mellitus Of Infancy

  • Permanent Neonatal Diabetes Mellitus 1

  • Diabetes Mellitus, Permanent, Of Infancy

  • Diabetes Mellitus, Permanent Neonatal 1

  • Developmental Delay-Epilepsy-Neonatal Diabetes Syndrome

  • Dend

  • Developmental Delay Epilepsy And Neonatal Diabetes

  • Diabetes Mellitus Permanent Neonatal With Neurologic Features

  • Diabetes Mellitus, Permanent Neonatal, Type 1
Silver-Russell Syndrome 1

  • Silver-Russell Syndrome

  • Russell-Silver Syndrome

  • Silver-Russell Dwarfism

  • Rss

  • SRS1

  • Srs

  • Silver Russell Dwarfism

  • Russell Silver Syndrome

  • Silver Russell Syndrome
Permanent Neonatal Diabetes Mellitus

  • Pndm

  • Permanent Diabetes Mellitus Of Infancy

  • Pdmi

  • Neonatal Diabetes Mellitus, Permanent
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Neonatal Diabetes

  • Neonatal Diabetes Mellitus

  • Diabetes Mellitus Syndrome In Newborn Infant

  • Ndm
Monogenic Diabetes
Maturity-Onset Diabetes Of The Young

  • MODY

  • Maturity Onset Diabetes Mellitus In Young

  • Mason-Type Diabetes

  • Mason Type Diabetes

  • Maturity Onset Diabetes Of The Young

  • Mody Syndrome

  • Diabetes Of The Young, Maturity-Onset
Diabetes Mellitus

  • Diabetes
Retroperitoneum Carcinoma

  • Retroperitoneal Cancer

  • Malignant Neoplasm Of Retroperitoneum And Peritoneum

  • Retroperitoneal Neoplasms

  • Carcinoma Of Retroperitoneum

  • Carcinoma Of The Retroperitoneum

  • Malignant Neoplasm Of Retroperitoneum

  • Malignant Retroperitoneal Cancer

  • Malignant Tumor Of Peritoneum And Retroperitoneum

  • Neoplasm Of Retroperitoneum

  • Neoplasm Of The Retroperitoneum

  • Retroperitoneal Neoplasm

  • Tumor Of Retroperitoneum

  • Malignant Retroperitoneal Tumour

  • Primary Malignant Neoplasm Of Retroperitoneum

  • Retroperitoneum Cancer
Beckwith-Wiedemann Syndrome

  • Wiedemann-Beckwith Syndrome

  • BWS

  • Exomphalos-Macroglossia-Gigantism Syndrome

  • Emg Syndrome

  • Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation

  • Emg Abnormality

  • Wbs

  • Exomphalos Macroglossia Gigantism Syndrome

  • Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation

  • Macroglossia Exomphalos Gigantism
Adult Syndrome

  • Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome

  • Acro Dermato Ungual Lacrimal Tooth Syndrome

  • Pigment Anomaly-Ectrodactyly-Hypodontia Syndrome

  • Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome

  • Adult
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06839 INS-IGF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus INS-IGF2 RGD RGD:2915