TMEM177 - transmembrane protein 177 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80775

About TMEM177

This gene has 6 transcripts (splice variants) and 180 orthologues. Ubiquitous expression in duodenum (RPKM 5.2), kidney (RPKM 5.0) and 25 other tissues.

Summary

Is integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM177 Products (3)

mRNA Protein Name
NM_001105198.2 NP_001098668.1 transmembrane protein 177
NM_001105199.2 NP_001098669.1 transmembrane protein 177
NM_030577.3 NP_085054.2 transmembrane protein 177

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
29154948 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
29154948 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 177

Related Diseases

Diseases Alias
Raynaud-Claes Syndrome

  • Mrx49

  • MRXSRC

  • Mental Retardation, X-Linked 49

  • Mrx15

  • Clcn4-Related X-Linked Intellectual Disability Syndrome

  • Mental Retardation, X-Linked 15

  • X-Linked Mental Retardation 15

  • X-Linked Mental Retardation 49

  • Mental Retardation, X-Linked-49
Mitochondrial Complex Iv Deficiency, Nuclear Type 1

  • Cytochrome C Oxidase Deficiency

  • Mitochondrial Complex Iv Deficiency

  • Cox Deficiency

  • Cytochrome-C Oxidase Deficiency Disease

  • MC1DN4

  • Cytochrome-C Oxidase Deficiency

  • MC4DN1

  • Mitochondrial Complex I Deficiency, Nuclear Type 4

  • Complex 4 Mitochondrial Respiratory Chain Deficiency

  • Complex Iv Deficiency

  • Mitochondrial Complex 1 Deficiency, Nuclear Type 4

  • Nuclear Type Mitochondrial Complex I Deficiency 4

  • Deficiency Of Mitochondrial Respiratory Chain Complex4

  • MT-C4D

  • Complex Iv Mitochondrial Respiratory Chain Deficiency

  • Lethal Neonatal Cardiomyopathy Hypertrophic Due To Cytochrome C Oxidase Deficiency

  • Mitochondrial Complex Iv Deficiency, Nuclear, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14686 TMEM177 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TMEM177 VGNC VGNC:79686
Rattus norvegicus TMEM177 RGD RGD:1310320
Bos taurus TMEM177 VGNC VGNC:36002
Canis familiaris TMEM177 VGNC VGNC:47503
Mus musculus TMEM177 MGD MGI:1913593
Others TMEM177 NCBI