2. Gene
  3. Ugcg - UDP-glucose ceramide glucosyltransferase Gene

Ugcg - UDP-glucose ceramide glucosyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 83626 | Gene type: protein coding

About Ugcg

Primary_assembly 5: 74,032,978-74,065,393 forward strand.mRatBN7.2:CM026978.1

This gene has 1 transcript (splice variant), 212 orthologues and is associated with 4 phenotypes. Biased expression in Adrenal (RPKM 17.6), Spleen (RPKM 95.4) and 9 other tissues.

Summary

Enables ceramide glucosyltransferase activity. Predicted to be involved in several processes, including cornified envelope assembly; glucosylceramide biosynthetic process; and skin development. Located in Golgi membrane. Is integral component of membrane. Orthologous to human UGCG (UDP-glucose ceramide glucosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Ugcg Products(1)

mRNA Protein Name
NM_031795.2 NP_113983.1 ceramide glucosyltransferase

Ugcg Protein Structure

Glucosylceramide_synthase

Glucosylceramide_synthase: cd02520 (50 - 279)

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  • 394 a.a.
Protein Preferred Names Protein Names

ceramide glucosyltransferase

GCS

GLCT-1

UDP-glucose:N-acylsphingosine D-glucosyltransferase

UDP-glucose:ceramide glycosyltransferase

glucosylceramide synthase

glycosylceramide synthase

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-132596 Tivanisiran Inhibitor / Phase 3
HY-148100 Emapticap pegol / Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15419 UGCG Human Pre-designed siRNA Set A / Unkown
HY-RS15420 Ugcg Mouse Pre-designed siRNA Set A / Unkown
HY-RS15421 Ugcg Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ugcg NCBI NCBI:7357