UMODL1 - uromodulin like 1 Gene
Species: Homo sapiens
About UMODL1
This gene has 14 transcripts (splice variants), 178 orthologues and 5 paralogues. Low expression observed in reference dataset.
Summary
Predicted to be an extracellular matrix structural constituent. Predicted to be involved in neutrophil migration. Predicted to act upstream of or within several processes, including adipose tissue development; cellular response to gonadotropin-releasing hormone; and regulation of ovarian follicle development. Predicted to be located in cytoplasm and external side of plasma membrane. Predicted to be integral component of membrane. Predicted to be active in apical plasma membrane; cell surface; and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
UMODL1 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001004416.3 | NP_001004416.3 | uromodulin-like 1 isoform 1 precursor |
| NM_001199527.3 | NP_001186456.2 | uromodulin-like 1 isoform 3 |
| NM_001199528.4 | NP_001186457.3 | uromodulin-like 1 isoform 4 |
| NM_173568.4 | NP_775839.4 | uromodulin-like 1 isoform 2 precursor |
UMODL1 Protein Structure
EMI: EMI domain (34 - 99)
WAP: WAP-type (Whey Acidic Protein) 'four-disulfide core' (117 - 157)
EGF_CA: Calcium-binding EGF domain (264 - 295)
SEA: SEA domain (396 - 485)
EGF_CA: Calcium-binding EGF domain (507 - 538)
SEA: SEA domain (791 - 863)
EGF_CA: Calcium-binding EGF domain (897 - 928)
Zona_pellucida: Zona pellucida-like domain (993 - 1234)
- 0
- 300
- 600
- 900
- 1200
- 1318 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
uromodulin-like 1 |
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Related Diseases
| Diseases | Alias | |
|---|---|---|
| Deafness, Autosomal Recessive 8 |
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| Myopia |
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| T-Cell Immunodeficiency With Thymic Aplasia |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Felis catus | UMODL1 | VGNC | VGNC:66819 |
| Bos taurus | UMODL1 | VGNC | VGNC:52839 |
| Rattus norvegicus | UMODL1 | RGD | RGD:1566039 |
| Mus musculus | UMODL1 | MGD | MGI:1929785 |
| Macaca mulatta | UMODL1 | VGNC | VGNC:78717 |
| Canis familiaris | UMODL1 | VGNC | VGNC:53049 |
| Others | UMODL1 | NCBI |