NAV3 - neuron navigator 3 Gene

Homo sapiens

Also known as POMFIL1; unc53H3; STEERIN3

Gene ID: 89795 | Gene type: protein coding

About NAV3

Cytogenetic location: 12q21.2 Genomic coordinates (GRCh38): 12:77,571,862-78,213,010 (from NCBI)

This gene has 16 transcripts (splice variants), 215 orthologues and 2 paralogues. Broad expression in brain (RPKM 3.5), ovary (RPKM 2.8) and 14 other tissues.

Summary

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008]

NAV3 Products(2)

mRNA	Protein	Name
NM_001024383.2	NP_001019554.1	neuron navigator 3 isoform 1
NM_014903.6	NP_055718.4	neuron navigator 3 isoform 2

NAV3 Protein Structure

AAA_14

0
400
800
1200
1600
2000
2385 a.a.

Protein Preferred Names

Protein Names

neuron navigator 3

pore membrane and/or filament interacting like protein 1

Related Diseases

Diseases

Alias

Panniculitis

Nodular Panniculitis

Sucrase-Isomaltase Deficiency, Congenital

Congenital Sucrase-Isomaltase Deficiency	CSID
Si Deficiency	Congenital Sucrose Intolerance
Disaccharide Intolerance	Sucrase-Isomaltase Deficiency
Disaccharide Intolerance I	Congenital Sucrose-Isomaltose Malabsorption
Sucrose-Isomaltose Malabsorption, Congenital	Sucrose Intolerance, Congenital
Congenital Sucrase-Isomaltose Malabsorption	Congenital Sucrose-Isomaltase Malabsorption
Disaccharide Intolerance, 1	Sucrose Intolerance Congenital
Sucrose-Isomaltase Malabsorption, Congenital	Disaccharidase Deficiency
Invertase Deficiency	Sucrase-Alpha-Dextrinase Deficiency
Disaccharide Intolerance Type I	Csid - [Congenital Sucrase-Isomaltase Deficiency]
Sucrose Intolerance Of Newborn	Sucrose Intolerance
Sucrase Deficiency	Disaccharide Malabsorption
Intestinal Disaccharidase Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09048	NAV3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	NAV3	VGNC	VGNC:43631
Mus musculus	NAV3	MGD	MGI:2183703
Macaca mulatta	NAV3	VGNC	VGNC:74969
Rattus norvegicus	NAV3	RGD	RGD:1306259
Felis catus	NAV3	VGNC	VGNC:63728
Bos taurus	NAV3	VGNC	VGNC:31892