PSTPIP2 - proline-serine-threonine phosphatase interacting protein 2 Gene

Also Known as MAYP

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 9050

About PSTPIP2

Cytogenetic location: 18q21.1 Genomic coordinates (GRCh38): 18:45,983,536-46,072,260 (from NCBI)

This gene has 6 transcripts (splice variants), 203 orthologues and 5 paralogues. Broad expression in bone marrow (RPKM 28.6), spleen (RPKM 27.4) and 17 other tissues.

Summary

Predicted to enable actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to be located in Cytoskeleton and membrane. Predicted to be active in actin filament; cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PSTPIP2 Products (1)

mRNA	Protein	Name
NM_024430.4	NP_077748.3	proline-serine-threonine phosphatase-interacting protein 2

PSTPIP2 Protein Structure

FCH

0
100
200
300
334 a.a.

Protein Preferred Names	Protein Names
proline-serine-threonine phosphatase-interacting protein 2	PEST phosphatase-interacting protein 2

Related Diseases

Diseases	Alias
Sapho Syndrome	Acquired Hyperostosis Syndrome Synovitis, Acne, Pustulosis Palmaris, Hyperostosis, Osteomyelitis Syndrome Synovitis Acne Pustulosis Hyperostosis Osteitis Synovitis, Acne, Pustlosis, Hyperostosis, And Osteomyelitis Synovitis-Acne-Pustulosis-Hyperostosis-Osteitis Syndrome Synovitis, Acne, Pustulosis, Hyperostosis, And Osteitis Syndrome Pustulo-Psoriatic Hyperostotic Spondylarthritis Sapho - [Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis] Syndrome
Chronic Recurrent Multifocal Osteomyelitis	Chronic Multifocal Osteomyelitis CRMO Cmo Cno/Crmo Chronic Nonbacterial Osteomyelitis/Chronic Recurrent Multifocal Osteomyelitis Osteomyelitis, Chronic Multifocal Multifocal Osteomyelitis, Chronic Chronic Osteomyelitis Chronic Multifocal Osteomyelitis, Unspecified Site Crmo - [Chronic Multifocal Osteomyelitis] Chronic Osteomyelitis With Draining Sinus, Unspecified Site Bone Fistula With Chronic Osteomyelitis
Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, And Acne	Papa Syndrome Fra Familial Recurrent Arthritis Pyogenic Arthritis, Pyoderma Gangrenosum And Acne PAPAS Pyogenic Arthritis-Pyoderma Gangrenosum-Acne Syndrome Pyogenic Arthritis, Pyoderma Gangrenosum, And Severe Cystic Acne Pyogenic Sterile Arthritis, Pyoderma Gangrenosum And Acne
Periostitis
Pustulosis Of Palm And Sole	Psoriasis Acropustulosis Palmoplantar Pustulosis Pustular Psoriasis Of The Palms And/Or Soles Pustulosis Of Palms And Soles Acrodermatitis Continua Of Hallopeau Generalized Pustular Psoriasis
Neutrophilic Dermatosis, Acute Febrile	Sweet Syndrome Acute Febrile Neutrophilic Dermatosis Ss AFND Pyrin-Associated Autoinflammatory Disease PAAND Gomm-Button Disease Sweet'S Syndrome Gomm Button Disease Sweets Syndrome Acromelic Frontonasal Dysostosis Sweet Disease
Erysipeloid	Infection Due To Erysipelothrix Rhusiopathiae Erysipelothrix Infection
Sebaceous Gland Disease	Sebaceous Gland Anomaly Sebaceous Gland Diseases

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11346	PSTPIP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PSTPIP2	VGNC	VGNC:76460
Bos taurus	PSTPIP2	VGNC	VGNC:33487
Canis familiaris	PSTPIP2	VGNC	VGNC:45128
Felis catus	PSTPIP2	VGNC	VGNC:69131
Rattus norvegicus	PSTPIP2	RGD	RGD:1563090
Mus musculus	PSTPIP2	MGD	MGI:1335088