SLC13A2 - solute carrier family 13 member 2 Gene

Homo sapiens

Also known as NaCT; NADC1; SDCT1; NaDC-1

Gene ID: 9058 | Gene type: protein coding

About SLC13A2

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:28,473,644-28,497,781 (from NCBI)

This gene has 6 transcripts (splice variants), 254 orthologues and 5 paralogues. Biased expression in duodenum (RPKM 49.7), small intestine (RPKM 41.0) and 4 other tissues.

Summary

The protein encoded by this gene is a sodium-coupled citrate transporter that is regulated by the chaperone activity of cyclophilin b. The encoded protein may play a role in the formation of kidney stones. [provided by RefSeq, Oct 2016]

SLC13A2 Products(4)

mRNA	Protein	Name
NM_001145975.2	NP_001139447.1	solute carrier family 13 member 2 isoform a
NM_001346683.2	NP_001333612.1	solute carrier family 13 member 2 isoform d
NM_001346684.2	NP_001333613.1	solute carrier family 13 member 2 isoform e
NM_003984.4	NP_003975.1	solute carrier family 13 member 2 isoform b

SLC13A2 Protein Structure

Na_sulph_symp

0
100
200
300
400
500
592 a.a.

Protein Preferred Names

Protein Names

solute carrier family 13 member 2

Na(+)-coupled citrate transporter

Related Diseases

Diseases

Alias

Nephrolithiasis, Uric Acid

Nephrolithiasis, Uric Acid, Susceptibility To	Uric Acid Urolithiasis
Uric Acid Nephrolithiasis	UAN
Acute Urate Nephropathy	Urolithiasis, Uric Acid
Urolithiasis, Uric Acid, Susceptibility To	Uric Acid Renal Calculus

Developmental And Epileptic Encephalopathy 25

Developmental And Epileptic Encephalopathy, 25	Dee25
Developmental And Epileptic Encephalopathy 25, With Amelogenesis Imperfecta	Early Infantile Epileptic Encephalopathy 25
Encephalopathy, Epileptic, Early Infantile, Type 25

Nephrolithiasis

Kidney Stones	Stone - Kidney/Ureter
Kidney Calculi

Hyperoxaluria, Primary, Type Ii

Primary Hyperoxaluria Type 2	D-Glycerate Dehydrogenase Deficiency
Glyoxylate Reductase/Hydroxypyruvate Reductase Deficiency	HP2
Oxalosis Ii	Glyceric Aciduria
L-Glyceric Aciduria	Primary Hyperoxaluria, Type Ii
Oxalosis 2	Hyperoxaluria Primary 2
Hyperoxaluria Primary Type Ii	Ph2
Primary Hyperoxaluria Type Ii

Sialolithiasis

Sialolith	Stone Of Salivary Gland Or Duct
Salivary Gland Calculi	Salivary Gland Stone
Calculus Of Salivary Gland Or Duct	Calculus Of Salivary Gland
Salivary Calculus	Salivary Gland Calculus
Salivary Stone	Salivary Duct Calculi
Sialodocholithiasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13006	SLC13A2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SLC13A2	VGNC	VGNC:65197
Rattus norvegicus	SLC13A2	RGD	RGD:61920
Macaca mulatta	SLC13A2	VGNC	VGNC:99256
Canis familiaris	SLC13A2	VGNC	VGNC:46228
Bos taurus	SLC13A2	VGNC	VGNC:34674
Mus musculus	SLC13A2	MGD	MGI:1276558

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