2. Gene
  3. FCMR - Fc mu receptor Gene

FCMR - Fc mu receptor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TOSO; FAIM3; FcmuR

Gene ID: 9214 | Gene type: protein coding

About FCMR

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:206,903,317-206,921,941 (from NCBI)

This gene has 10 transcripts (splice variants), 92 orthologues and 13 paralogues. Biased expression in lymph node (RPKM 59.4), spleen (RPKM 52.0) and 6 other tissues.

Summary

Fc Receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]

FCMR Products(18)

mRNA Protein Name
NM_001142473.2 NP_001135945.1 fas apoptotic inhibitory molecule 3 isoform b
NM_001193338.2 NP_001180267.1 fas apoptotic inhibitory molecule 3 isoform c precursor
NM_001405862.1 NP_001392791.1 fas apoptotic inhibitory molecule 3 isoform d
NM_001405863.1 NP_001392792.1 fas apoptotic inhibitory molecule 3 isoform d
NM_001405864.1 NP_001392793.1 fas apoptotic inhibitory molecule 3 isoform e precursor
NM_001405865.1 NP_001392794.1 fas apoptotic inhibitory molecule 3 isoform e precursor
NM_001405866.1 NP_001392795.1 fas apoptotic inhibitory molecule 3 isoform f precursor
NM_001405867.1 NP_001392796.1 fas apoptotic inhibitory molecule 3 isoform g precursor
NM_001405868.1 NP_001392797.1 fas apoptotic inhibitory molecule 3 isoform g precursor
NM_001405871.1 NP_001392800.1 fas apoptotic inhibitory molecule 3 isoform a precursor
NM_001405886.1 NP_001392815.1 fas apoptotic inhibitory molecule 3 isoform h
NM_001405887.1 NP_001392816.1 fas apoptotic inhibitory molecule 3 isoform b
NM_001405888.1 NP_001392817.1 fas apoptotic inhibitory molecule 3 isoform j
NM_001405889.1 NP_001392818.1 fas apoptotic inhibitory molecule 3 isoform k precursor
NM_001405890.1 NP_001392819.1 fas apoptotic inhibitory molecule 3 isoform l
NM_001405891.1 NP_001392820.1 fas apoptotic inhibitory molecule 3 isoform m
NM_001405892.1 NP_001392821.1 fas apoptotic inhibitory molecule 3 isoform n precursor
NM_005449.5 NP_005440.1 fas apoptotic inhibitory molecule 3 isoform a precursor

FCMR Protein Structure

ig

ig: Immunoglobulin domain (30 - 105)

  • 0
  • 100
  • 200
  • 300
  • 390 a.a.
Protein Preferred Names Protein Names

fas apoptotic inhibitory molecule 3

Fc fragment of IgM receptor

Recombinant FCMR Proteins

Cat. No. Product Name Accession Purity
HY-P77364 FCMR/FAIM3 Protein, Human (HEK293, Fc) O60667/NP_005440.1 (R18-G251) ≥95%

Related Diseases

Diseases Alias
Immunodeficiency 54

Natural Killer Cell Deficiency, Familial Isolated

Primary Immunodeficiency With Natural-Killer Cell Deficiency And Adrenal Insufficiency

IMD54

Nkcd

Natural Killer Cell And Glucocorticoid Deficiency With Dna Repair Defect

Nkgcd

Familial Isolated Natural Killer Cell Deficiency

Primary Immunodeficiency Due To Mcm4 Deficiency
Pinguecula
Conjunctival Degeneration
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04838 FCMR Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta FCMR VGNC VGNC:72507
Rattus norvegicus FCMR RGD RGD:1359282
Canis familiaris FCMR VGNC VGNC:40808
Felis catus FCMR VGNC VGNC:62214
Bos taurus FCMR VGNC VGNC:28938
Mus musculus FCMR MGD MGI:1916419