Cat. No.: HY-W089845

Heneicosane

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Based on 1 publication(s) in Google Scholar

Heneicosane is a royal-specific pheromone of insects (such as subterranean termites) and is an identification signal for queens and kings in termites. Heneicosane mediates royal recognition and the maintenance of social division of labor by being sensed by worker ants and triggering vibrations and antennal behaviors. Heneicosane can exert anti-inflammatory, analgesic and antipyretic activities by inhibiting the release of inflammatory mediators (such as prostaglandins and cytokines). At the same time, Heneicosane can also inhibit the mycelial growth of aflatoxin-producing fungi and inhibit the production of aflatoxin. Heneicosane can be used in insect chemical ecology research to analyze the regulatory mechanism of termite social behavior, and is also a potential target for new anti-inflammatory drugs.

For research use only. We do not sell to patients.

Purity: 99.72%
CAS No.: 629-94-7
Formula: C₂₁H₄₄
Molecular Weight:296.57

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Heneicosane Chemical Structure

CAS No.: 629-94-7

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
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Biological Activity

Description

In Vitro

Heneicosane is a hydrocarbon specific to the royal family (queens and kings) of the subterranean termite Reticulitermes flavipes. Its content in the royal family is significantly higher than that in the worker termites. Heneicosane is the first confirmed pheromone for the royal family recognition of termites^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Heneicosane (0.1-10 μg/glass dummy) alone or in combination with worker ant cuticle extracts, dose-dependently induces shaking and antennal behavior in worker ants, the effects of which are consistent with those of natural royal individuals, confirming its biological activity as a royal recognition signal^[1].
Heneicosane (1000 mg/kg; oral; once daily; for 14 consecutive days) does not cause death, behavioral abnormalities or changes in visceral morphology in the Sprague-Dawley rat acute toxicity model, confirming that it had no significant toxicity to rats at a dose of 1000 mg/kg^[2].
Heneicosane (5-10 mg/kg; oral; single dose) significantly inhibits acetic acid-induced writhing reaction and formaldehyde-induced paw licking behavior (late stage) in rat models of acetic acid/formaldehyde-induced pain, carrageenan-induced inflammation, and yeast-induced fever, without significant inhibitory effect on carrageenan-induced paw edema and yeast-induced temperature increase^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 629-94-7
Appearance Solid
Molecular Weight 296.57
Formula C₂₁H₄₄
Color White to off-white
SMILES

CCCCCCCCCCCCCCCCCCCCC
Structure Classification
- Others
Initial Source
- Plants
- other families
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (1)

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Planta Med

Discovery and characterization of panaxatriol as a novel thrombin inhibitor from Panax notoginseng using combination of computational and experimental approach. [Abstract]

2024 Aug;90(10):801-809. PMID: 38838717

Solvent & Solubility

In Vitro:

Ethanol : 10 mg/mL (33.72 mM; ultrasonic and warming and heat to 60°C)

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Preparing Stock Solutions

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Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

3.3719 mL

16.8594 mL

33.7189 mL

5 mM

0.6744 mL

3.3719 mL

6.7438 mL

10 mM

0.3372 mL

1.6859 mL

3.3719 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Working solution concentration: 0.22 mg/mL

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Colin F Funaro, et al. Identification of a queen and king recognition pheromone in the subterranean termite Reticulitermes flavipes. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3888-3893. [Content Brief]

[2]. Okechukwu P N. Evaluation of anti-inflammatory, analgesic, antipyretic effect of eicosane, pentadecane, octacosane, and heneicosane. Asian J. Pharamath. Clin. Res, 2020, 13.

[3]. Boukaew S, et al. Efficacy of volatile compounds from Streptomyces philanthi RL-1-178 as a biofumigant for controlling growth and aflatoxin production of the two aflatoxin-producing fungi on stored soybean seeds. J Appl Microbiol. 2020 Sep;129(3):652-664. [Content Brief]

[4]. Prathipkumar S, et al. Biogenic-mediated silver nanoparticles using heneicosane and their enhanced antimicrobial, antiproliferative, sensing capability and photocatalytic potential. Applied Nanoscience, 2023, 13(9): 5839-5849.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
Ethanol	1 mM	3.3719 mL	16.8594 mL	33.7189 mL	84.2971 mL
	5 mM	0.6744 mL	3.3719 mL	6.7438 mL	16.8594 mL
	10 mM	0.3372 mL	1.6859 mL	3.3719 mL	8.4297 mL
	15 mM	0.2248 mL	1.1240 mL	2.2479 mL	5.6198 mL
	20 mM	0.1686 mL	0.8430 mL	1.6859 mL	4.2149 mL
	25 mM	0.1349 mL	0.6744 mL	1.3488 mL	3.3719 mL
	30 mM	0.1124 mL	0.5620 mL	1.1240 mL	2.8099 mL

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Heneicosane

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Publications Citing Use of MedChemExpress (MCE) Heneicosane

Biological Activity

Chemical Information

Publications (1)

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

Heneicosane Related Classifications

Cat. No.: HY-W089845