Hydroxydione
Hydroxydione has an effect of general anesthetic. Hydroxydione is a neuroactive steroid it can be used for anaesthesia related research.
For research use only. We do not sell to patients.
- CAS No.: 303-01-5
- Formula: C21H32O3
- Molecular Weight:332.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Cats with chloralose 60 to 80 mg/kg[2]
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Dosage:5-100 mg/kg
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Administration:Intravenous injection; 5-100 mg/kg once
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Result:Produce severe respiratory depression, but showed no effect on the tibialis in response to excitation of its motor nerve under the condition of chloralose. Produced the usual substantial sustained hypotension seen in chloralosed cats to response the nictitating membrane to preganglionic excitation with a dose of 10 mg/kg. Repressed the respiration in chloralosed cats after a rapid injection.
Chemical Information
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CAS No. 303-01-5
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Molecular Weight 332.48
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Formula C21H32O3
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SMILES
C[C@@]12[C@](CC[C@@H]2C(CO)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](CC(CC4)=O)([H])CC3)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. RUMKE CL. The influence of drugs on the duration of hexobarbital and hydroxydione narcosis in mice. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1963;244:519-30. [Content Brief]
[2]. LERMAN LH, PATON WD. Experiments on the pharmacology of hydroxydione sodium succinate. Br J Pharmacol Chemother. 1960 Sep;15(3):458-65. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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