YM-I-26
YM-I-26 is a selective NLRP3 inflammasome inhibitor. YM-I-26 enhances the phagocytosis of β-amyloid protein by mouse microglial BV2 cells and inhibits the production of IL-1β and IL-10. YM-I-26 can be used to study the immunomodulatory activity associated with inflammation.
For research use only. We do not sell to patients.
- CAS No.: 2585015-90-1
- Formula: C28H33ClN2O5S2
- Molecular Weight:577.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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IL-1β |
IL-10 |
Chemical Information
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CAS No. 2585015-90-1
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Molecular Weight 577.16
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Formula C28H33ClN2O5S2
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SMILES
O=S(C1=CC=C(CCN(CC2=C(OCCC)C=CC(Cl)=C2)C(CC3=CSC=C3)=O)C=C1)(N4CCOCC4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)