Srpx - sushi-repeat-containing protein Gene

Also Known as drs; DRS-1; DRS-2; drs-1; drs-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 51795

Summary

Acts upstream of or within several processes, including negative regulation of cell proliferation involved in contact inhibition; phagolysosome assembly; and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Located in autophagosome and endoplasmic reticulum. Is expressed in several structures, including otic capsule and skeleton. Orthologous to human SRPX (sushi repeat containing protein X-linked). [provided by Alliance of Genome Resources, Apr 2022]

Srpx Products (2)

mRNA Protein Name
NM_001365087.1 NP_001352016.1 sushi-repeat-containing protein SRPX isoform 2 precursor
NM_016911.5 NP_058607.1 sushi-repeat-containing protein SRPX isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19368996 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within autophagy IMP
IMP: Inferred from mutant phenotype
19368996 MGI
acts upstream of or within negative regulation of cell proliferation involved in contact inhibition IDA
IDA: Inferred from direct assay
12049817 MGI
acts upstream of or within phagolysosome assembly IMP
IMP: Inferred from mutant phenotype
19368996 MGI
acts upstream of or within positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IMP
IMP: Inferred from mutant phenotype
17088259 MGI
acts upstream of or within response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
17088259 MGI
Cellular Component GO Annotation Evidence References Source
located in autophagosome IDA
IDA: Inferred from direct assay
19368996 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
19368996 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sushi-repeat-containing protein SRPX

  • sushi-repeat-containing protein, X-chromosome

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13782 SRPX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13783 SRPX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17995 Srpx2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19642 Srpx Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24466 Srpx2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26135 Srpx Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srpx NCBI NCBI:8406