RLF - RLF zinc finger Gene

Also Known as ZN-15L; ZNF292L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6018

About RLF

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:40,161,387-40,240,921 (from NCBI)

This gene has 1 transcript (splice variant), 214 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 13.7), testis (RPKM 7.9) and 25 other tissues.

Summary

Predicted to enable DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within histone H3-K4 monomethylation and regulation of DNA methylation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RLF Products (1)

mRNA Protein Name
NM_012421.4 NP_036553.2 zinc finger protein Rlf

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10545207 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RLF Protein Structure

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (671 - 696)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (954 - 979)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (1172 - 1195)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1310 - 1335)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1800
  • 1914 a.a.
Protein Preferred Names Protein Names

zinc finger protein Rlf

  • Zn-15 related

RLF Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
RLF Q13129 Q99IB8-PRO_0000045603 Hepatitis C virus Q99IB8-PRO_0000045603
Y2H
24136289
Cross
RLF Q13129 Q99IB8-PRO_0000045603 Hepatitis C virus Q99IB8-PRO_0000045603
Pull Down
24136289
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Left Ventricular Noncompaction

  • Noncompaction Cardiomyopathy

  • Left Ventricular Hypertrabeculation

  • Lvnc

  • Spongy Myocardium

  • Isolated Noncompaction Of The Ventricular Myocardium

  • Left Ventricular Myocardial Noncompaction Cardiomyopathy

  • Fetal Myocardium

  • Honeycomb Myocardium

  • Hypertrabeculation Syndrome

  • Left Ventricular Non-Compaction

  • Lvht

  • Non-Compaction Of The Left Ventricular Myocardium

  • Ventricular Noncompaction, Left

  • Non-Compaction Cardiomyopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06840 INSL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12007 RLF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18330 Rlf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20428 Insl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21420 Rgl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24809 Rlf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26937 Insl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus RLF VGNC VGNC:64647
Bos taurus RLF VGNC VGNC:33990
Canis familiaris RLF VGNC VGNC:45604
Macaca mulatta RLF VGNC VGNC:76699
Rattus norvegicus RLF RGD RGD:1305297
Mus musculus RLF MGD MGI:1924705
Others RLF NCBI