AGN-745
AGN-745 is a chemically modified siRNA targeted to VEGFR-1. It is used for the study of Macular degeneration.
For research use only. We do not sell to patients.
- CAS No.: 1255908-66-7
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1255908-66-7
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SMILES
[AGN-745]
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Synonyms
AGN-211745; Sirna-027
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jiang J, Zhang X, Tang Y, Li S, Chen J. Progress on ocular siRNA gene-silencing therapy and drug delivery systems. Fundam Clin Pharmacol. 2021;35(1):4-24. [Content Brief]
[2]. Shen J, Samul R, Silva RL, et al. Suppression of ocular neovascularization with siRNA targeted to VEGF receptor 1. Gene Ther. 2006;13(3):225-234. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)