P2ry2 - purinergic receptor P2Y, G-protein coupled 2 Gene

Also Known as P2U1; P2Y2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18442

About P2ry2

Chromosome 7: 100,645,775-100,662,073 reverse strand.GRCm39:CM001000.3

This gene has 6 transcripts (splice variants), 201 orthologues, 13 paralogues and is associated with 4 phenotypes. Broad expression in heart adult (RPKM 12.3), small intestine adult (RPKM 1.9) and 18 other tissues.

Summary

Predicted to enable A1 Adenosine Receptor binding activity; ATP binding activity; and G protein-coupled UTP receptor activity. Acts upstream of or within positive regulation of mucus secretion. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to colocalize with early endosome; lysosome; and mitochondrion. Orthologous to human P2RY2 (purinergic receptor P2Y2). [provided by Alliance of Genome Resources, Apr 2022]

P2ry2 Products (3)

mRNA Protein Name
NM_008773.4 NP_032799.2 P2Y purinoceptor 2
NM_001302346.1 NP_001289275.1 P2Y purinoceptor 2
NM_001302347.1 NP_001289276.1 P2Y purinoceptor 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
17728398 MGI
acts upstream of mucus secretion IMP
IMP: Inferred from mutant phenotype
17728398 MGI
acts upstream of or within positive regulation of mucus secretion IMP
IMP: Inferred from mutant phenotype
17728398 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

P2ry2 Protein Structure

7tmA_P2Y2

7tmA_P2Y2: cd15373 (33 - 60)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (33 - 316)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (67 - 92)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (105 - 135)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (147 - 169)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (194 - 223)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (237 - 267)

7tmA_P2Y2

7tmA_P2Y2: cd15373 (284 - 309)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 2

  • ATP receptor

  • P2U purinoceptor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09928 P2RY2 Human Pre-designed siRNA Set A / Unkown
HY-RS09929 P2ry2 Mouse Pre-designed siRNA Set A / Unkown
HY-RS09930 P2ry2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2ry2 NCBI NCBI:5029