178469-71-1
178469-71-1
Chemical Structure
KY-455
- CAS 番号: 178469-71-1
- Formula:C20H32N2O
- Molecular Weight:316.48
InChIKey: HYEIHNVWTVQZFH-UHFFFAOYSA-N
SMILES: O=C(C(C)(C)C)NC1=C(C)C=C(C)C2=C1N(CCCCC)CC2
Biological Activity: KY-455 is a novel inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). KY-455 inhibita rabbit intestinal, hepatic, macrophage and adrenal ACAT with IC50 values of 0.4, 0.9, 2.9 and 4.1 μmol/L, respectively.
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KY-455 | KY-455 is a novel inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). KY-455 inhibita rabbit intestinal, hepatic, macrophage and adrenal ACAT with IC50 values of 0.4, 0.9, 2.9 and 4.1 μmol/L, respectively. | |||||||||||||||||||||
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Keywords
