Chkb - choline kinase beta Gene

Also Known as Ck; Ek; Ckb; Chkl; Chetk; Ck/Ek; Ckekb; Ck/Ek-beta

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 12651

Summary

Enables Choline Kinase activity. Acts upstream of or within muscle organ development and phosphatidylcholine biosynthetic process. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; cranium; heart; and sensory organ. Used to study megaconial type congenital muscular dystrophy. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to human CHKB (Choline Kinase beta). [provided by Alliance of Genome Resources, Apr 2022]

Chkb Products (1)

mRNA Protein Name
NM_007692.6 NP_031718.1 choline/ethanolamine kinase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables choline kinase activity IMP
IMP: Inferred from mutant phenotype
16371353 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within muscle organ development IMP
IMP: Inferred from mutant phenotype
16371353 MGI
acts upstream of or within phosphatidylcholine biosynthetic process IMP
IMP: Inferred from mutant phenotype
16371353 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

choline/ethanolamine kinase

  • choline/ethanolamine kinase-b

  • choline/ethanolaminekinase

  • ethanolamine kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02634 CHKB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22118 Chkb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28640 Chkb Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Chkb NCBI NCBI:1120