A2m - alpha-2-macroglobulin Gene

Also Known as A2mp

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 232345

Summary

Predicted to enable several functions, including cytokine binding activity; growth factor binding activity; and serine-type endopeptidase inhibitor activity. Acts upstream of or within stem cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; embryo mesenchyme; liver; meninges; and retina. Human ortholog(s) of this gene implicated in COVID-19; background diabetic retinopathy; multiple sclerosis; neurodegenerative disease (multiple); and obstructive lung disease. Orthologous to human A2M (alpha-2-macroglobulin). [provided by Alliance of Genome Resources, Apr 2022]

A2m Products (1)

mRNA Protein Name
NM_175628.3 NP_783327.2 alpha-2-macroglobulin-P precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
17920016 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within stem cell differentiation IDA
IDA: Inferred from direct assay
19796622 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-2-macroglobulin-P

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS00010 A2M Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-CE00893 2M2PE-CoA / Unkown
HY-RS18322 A2m Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19112 Pzp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24800 A2m Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens A2m NCBI NCBI:2