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ZBTB11 - zinc finger and BTB domain containing 11 Gene

Also Known as MRT69; ZNF913; ZNF-U69274

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 27107

About ZBTB11

Cytogenetic location: 3q12.3 Genomic coordinates (GRCh38): 3:101,648,889-101,677,132 (from NCBI)

This gene has 15 transcripts (splice variants), 213 orthologues, 38 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 8.1), testis (RPKM 5.9) and 25 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Located in nucleoplasm. Implicated in autosomal recessive non-syndromic intellectual disability. [provided by Alliance of Genome Resources, Apr 2022]

ZBTB11 Products (1)

mRNA	Protein	Name
NM_014415.4	NP_055230.2	zinc finger and BTB domain-containing protein 11

ZBTB11 Protein Structure

BTB

zf-C2H2

zf-C2H2_4

zf-H2C2_2

zf-C2H2

zf-H2C2_2

0
200
400
600
800
1000
1053 a.a.

Protein Preferred Names	Protein Names
zinc finger and BTB domain-containing protein 11

関連疾患

Diseases	Alias
Intellectual Developmental Disorder, Autosomal Recessive 69	MRT69 Mental Retardation, Autosomal Recessive 69 Autosomal Recessive Intellectual Developmental Disorder 69
Chromosome 3q13.31 Deletion Syndrome	3q13 Microdeletion Syndrome Monosomy 3q13 Chromosome 3, Monosomy 3q13 Del(3)(Q13)
Syndromic Intellectual Disability
Galactosemia Iii	Galactose Epimerase Deficiency Gale Deficiency Udp-Galactose-4-Epimerase Deficiency Epimerase Deficiency Galactosemia Galactosemia Type 3 Gale-D Uridine Diphosphate Galactose-4-Epimerase Deficiency GALAC3 Galactosemia 3 Generalized Uridine Diphosphate Galactose-4-Epimerase Deficiency Erythrocyte Uridine Diphosphate Galactose-4-Epimerase Deficiency Galactosemia Type Iii Udp-Galactose-4'-Epimerase Deficiency Generalized Galactose Epimerase Deficiency Generalized Gale Deficiency Generalized Gale-D Generalized Udp-Galactose-4-Epimerase Deficiency Generalized Epimerase Deficiency Galactosemia Erythrocyte Galactose Epimerase Deficiency Erythrocyte Gale Deficiency Erythrocyte Gale-D Erythrocyte Udp-Galactose-4-Epimerase Deficiency Erythrocyte Epimerase Deficiency Galactosemia Galactosemias Classical Galactosemia Udpglucose 4-Epimerase Deficiency Disease
Combined Malonic And Methylmalonic Aciduria	CMAMMA Combined Malonic And Methylmalonic Acidemia Aciduria, Combined Malonic And Methylmalonic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-161767	JWJ-01-306	Inhibitor	/	Unkown
HY-RS15961	ZBTB11 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22783	Rpl24 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Rattus norvegicus	ZBTB11	RGD	RGD:1308275
Mus musculus	ZBTB11	MGD	MGI:2443876
Felis catus	ZBTB11	VGNC	VGNC:102871
Bos taurus	ZBTB11	VGNC	VGNC:37059
Macaca mulatta	ZBTB11	VGNC	VGNC:82563
Canis familiaris	ZBTB11	VGNC	VGNC:48521
Others	ZBTB11	NCBI