CISD3 - CDGSH iron sulfur domain 3 Gene

Also Known as MiNT; Miner2

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 284106

About CISD3

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,730,341-38,735,605 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 94 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 15.7), small intestine (RPKM 14.3) and 25 other tissues.

Summary

CISD3 is a member of the CDGSH domain-containing family, which may play a role in regulating electron transport and Oxidative Phosphorylation (Wiley et al., 2007 [PubMed 17376863]).[supplied by OMIM, Apr 2008]

CISD3 Products (1)

mRNA Protein Name
NM_001136498.2 NP_001129970.1 CDGSH iron-sulfur domain-containing protein 3, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables 2 iron, 2 sulfur cluster binding IDA
IDA: Inferred from direct assay
29259115 GOA
enables metal ion binding IDA
IDA: Inferred from direct assay
29259115 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in protein maturation by [2Fe-2S] cluster transfer IDA
IDA: Inferred from direct assay
29259115 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in mitochondrion IDA
IDA: Inferred from direct assay
17376863 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CISD3 Protein Structure

zf-CDGSH

zf-CDGSH: Iron-binding zinc finger CDGSH type (44 - 75)

zf-CDGSH

zf-CDGSH: Iron-binding zinc finger CDGSH type (82 - 114)

  • 0
  • 100
  • 127 a.a.
Protein Preferred Names Protein Names

CDGSH iron-sulfur domain-containing protein 3, mitochondrial

  • mitoNEET related 2

関連疾患

Diseases Alias
Wolfram Syndrome 2

  • WFS2
Wolfram Syndrome

  • Didmoad Syndrome

  • Didmoad

  • Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness

  • Wfs

  • Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, And Deafness

  • Didmoadud

  • Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Deafness Syndrome

  • Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Hearing Loss Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02725 CISD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus CISD3 RGD RGD:1559720
Mus musculus CISD3 MGD MGI:101788
Bos taurus CISD3 VGNC VGNC:27373
Canis familiaris CISD3 VGNC VGNC:39280
Others CISD3 NCBI