Idua - alpha-L-iduronidase Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 360904

Summary

Enables L-iduronidase activity and signaling receptor binding activity. Involved in glycosaminoglycan catabolic process. Located in coated vesicle and lysosome. Biomarker of gastric ulcer. Human ortholog(s) of this gene implicated in Scheie syndrome; mucopolysaccharidosis I; mucopolysaccharidosis Ih; and mucopolysaccharidosis Ih/s. Orthologous to human IDUA (alpha-L-iduronidase). [provided by Alliance of Genome Resources, Apr 2022]

Idua Products (1)

mRNA Protein Name
NM_001172084.1 NP_001165555.1 alpha-L-iduronidase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables L-iduronidase activity IDA
IDA: Inferred from direct assay
6138357 RGD
enables signaling receptor binding IMP
IMP: Inferred from mutant phenotype
6138357 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in glycosaminoglycan catabolic process IDA
IDA: Inferred from direct assay
6138357 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-L-iduronidase

  • Idual

  • iduronidase, alpha-L-

  • iduronidase, alpha-L-like

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

阻害性抗体 (2)
製品番号 製品名 製品効果
純度 Phase
HY-P99530 Valanafusp alfa 98.42% Phase 2
HY-P99694 Lepunafusp alfa Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-W654272 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium 98.77% Unkown
HY-RS06546 IDUA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17959 Idua Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24430 Idua Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Idua NCBI NCBI:3425