SLC46A2 - solute carrier family 46 member 2 Gene

Also Known as Ly110; TSCOT

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 57864

About SLC46A2

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:112,878,920-112,890,876 (from NCBI)

This gene has 2 transcripts (splice variants), 227 orthologues and 2 paralogues. Biased expression in lung (RPKM 9.2), skin (RPKM 5.1) and 6 other tissues.

Summary

Predicted to enable transmembrane transporter activity. Involved in positive regulation of nucleotide-binding activity oligomerization domain containing 1 signaling pathway. Predicted to be located in cell surface and plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC46A2 Products (1)

mRNA Protein Name
NM_033051.4 NP_149040.3 thymic stromal cotransporter homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables cyclic-GMP-AMP transmembrane transporter activity IDA
IDA: Inferred from direct assay
34235268 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in cyclic-GMP-AMP transmembrane import across plasma membrane IDA
IDA: Inferred from direct assay
34235268 GOA
involved in positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway IMP
IMP: Inferred from mutant phenotype
28539433 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in plasma membrane IDA
IDA: Inferred from direct assay
34235268 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC46A2 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (85 - 420)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 475 a.a.
Protein Preferred Names Protein Names

thymic stromal cotransporter homolog

  • thymic stromal co-transporter

関連疾患

Diseases Alias
Folate Malabsorption, Hereditary

  • Hereditary Folate Malabsorption

  • Congenital Defect Of Folate Absorption

  • Congenital Folate Malabsorption

  • Folic Acid Transport Defect

  • HFM
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS13261 SLC46A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Mus musculus SLC46A2 MGD MGI:1353616
Felis catus SLC46A2 VGNC VGNC:65380
Rattus norvegicus SLC46A2 RGD RGD:1310485
Macaca mulatta SLC46A2 VGNC VGNC:77714
Canis familiaris SLC46A2 VGNC VGNC:46427
Bos taurus SLC46A2 VGNC VGNC:34885
Others SLC46A2 NCBI