TMC5 - transmembrane channel like 5 Gene
生物種: Homo sapiens
遺伝子タイプ: protein coding
遺伝子ID: 79838
About TMC5
Cytogenetic location: 16p12.3
Genomic coordinates (GRCh38): 16:19,410,539-19,499,113 (from NCBI)
This gene has 11 transcripts (splice variants), 214 orthologues and 7 paralogues. Biased expression in small intestine (RPKM 21.9), stomach (RPKM 18.3) and 10 other tissues.
Summary
Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in ion transmembrane transport. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
TMC5 Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001105248.1 | NP_001098718.1 | transmembrane channel-like protein 5 isoform a |
| NM_001105249.1 | NP_001098719.1 | transmembrane channel-like protein 5 isoform b |
| NM_001261841.2 | NP_001248770.1 | transmembrane channel-like protein 5 isoform a |
| NM_001308161.1 | NP_001295090.1 | transmembrane channel-like protein 5 isoform d |
| NM_024780.5 | NP_079056.2 | transmembrane channel-like protein 5 isoform c |
TMC5 Protein Structure
TMC
TMC: TMC domain (724 - 830)
- 0
- 200
- 400
- 600
- 800
- 1006 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
transmembrane channel-like protein 5 |
|
関連疾患
| Diseases | Alias | |
|---|---|---|
| Chromophobe Renal Cell Carcinoma |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| 製品番号 | 製品名 |
製品効果
|
純度 |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS14625 | TMC5 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Felis catus | TMC5 | VGNC | VGNC:66236 |
| Mus musculus | TMC5 | MGD | MGI:1921674 |
| Canis familiaris | TMC5 | VGNC | VGNC:47424 |
| Macaca mulatta | TMC5 | VGNC | VGNC:79366 |
| Bos taurus | TMC5 | VGNC | VGNC:35921 |
| Rattus norvegicus | TMC5 | RGD | RGD:1307037 |
| Others | TMC5 | NCBI |
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