COL21A1 - collagen type XXI alpha 1 chain Gene

Also Known as FP633; COLA1L

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 81578

About COL21A1

Cytogenetic location: 6p12.1 Genomic coordinates (GRCh38): 6:56,056,590-56,394,128 (from NCBI)

This gene has 12 transcripts (splice variants), 109 orthologues and 37 paralogues. Broad expression in placenta (RPKM 9.8), heart (RPKM 8.6) and 16 other tissues.

Summary

This gene encodes the alpha chain of type XXI Collagen, a member of the FACIT (fibril-associated collagens with interrupted helices) Collagen family. Type XXI Collagen is localized to tissues containing type I Collagen and maintains the integrity of the extracellular matrix. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

COL21A1 Products (5)

mRNA Protein Name
NM_001318751.2 NP_001305680.1 collagen alpha-1(XXI) chain isoform a precursor
NM_001318752.2 NP_001305681.1 collagen alpha-1(XXI) chain isoform b precursor
NM_001318753.2 NP_001305682.1 collagen alpha-1(XXI) chain isoform c
NM_001318754.2 NP_001305683.1 collagen alpha-1(XXI) chain isoform d
NM_030820.4 NP_110447.2 collagen alpha-1(XXI) chain isoform a precursor

COL21A1 Protein Structure

VWA

VWA: von Willebrand factor type A domain (37 - 206)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (448 - 500)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (486 - 542)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (536 - 594)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (681 - 733)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (731 - 787)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (825 - 882)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (884 - 934)

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  • 200
  • 400
  • 600
  • 800
  • 957 a.a.
Protein Preferred Names Protein Names

collagen alpha-1(XXI) chain

  • alpha 1 chain-like collagen

Recombinant COL21A1 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P70094 COL21A1 Protein, Human (HEK293, His) Q96P44-1 (E23-Y957) ≥ 95%, as determined by reducing SDS-PAGE.

関連疾患

Diseases Alias
Ullrich Congenital Muscular Dystrophy 1

  • Ullrich Congenital Muscular Dystrophy

  • Ullrich Disease

  • Ucmd

  • Ullrich Scleroatonic Muscular Dystrophy

  • Scleroatonic Muscular Dystrophy

  • UCMD1

  • Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 22

  • Lgmdr22

  • Muscular Dystrophy, Scleroatonic

  • Late Onset Scleroatonic Familial Myopathy

  • Congenital Muscular Dystrophy, Ullrich Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02973 COL21A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown