LSM10 - LSM10, U7 small nuclear RNA associated Gene

Also Known as MST074; MSTP074

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 84967

About LSM10

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:36,393,436-36,397,908 (from NCBI)

This gene has 3 transcripts (splice variants) and 183 orthologues. Ubiquitous expression in lymph node (RPKM 20.1), spleen (RPKM 17.7) and 25 other tissues.

Summary

Enables U7 snRNA binding activity. Involved in positive regulation of G1/S transition of mitotic cell cycle. Located in Cajal body. Part of U7 snRNP. [provided by Alliance of Genome Resources, Apr 2022]

LSM10 Products (1)

mRNA Protein Name
NM_032881.3 NP_116270.1 U7 snRNA-associated Sm-like protein LSm10

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables U7 snRNA binding IPI
IPI: Inferred from physical interaction
18082603 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12975319 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in positive regulation of G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
16914750 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in Cajal body IDA
IDA: Inferred from direct assay
11574479 GOA
part of U7 snRNP IDA
IDA: Inferred from direct assay
11574479 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LSM10 Protein Structure

LSM

LSM: LSM domain (21 - 83)

  • 0
  • 100
  • 123 a.a.
Protein Preferred Names Protein Names

U7 snRNA-associated Sm-like protein LSm10

  • U7 snRNP-specific Sm-like protein LSM10

LSM10 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
LSM10 Q969L4 LSM3 Homo sapiens P62310
Y2H Array
19060904
Intra
LSM10 Q969L4 LSM3 Homo sapiens P62310
Y2H Pooling
19060904
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Cerebrooculofacioskeletal Syndrome 2

  • COFS2

  • Cerebro-Oculo-Facio-Skeletal Syndrome 2

  • Cofs Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS07853 LSM10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus LSM10 VGNC VGNC:31051
Mus musculus LSM10 MGD MGI:2151045
Macaca mulatta LSM10 VGNC VGNC:74307
Rattus norvegicus LSM10 RGD RGD:1584914
Felis catus LSM10 VGNC VGNC:107577
Canis familiaris LSM10 VGNC VGNC:42839
Others LSM10 NCBI